Biological Sciences

Are stressed-out brain cells the root cause of neurodegenerative disease?

February 14, 2024

Illustration of a brain cell with blue squiggles around a purple circleMany neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases, are characterized by the accumulation of protein clumps, or aggregates, in the brain, which has led scientists to assume that the protein tangles kill brain cells. The search for treatments that break up and remove these tangled proteins has had little success, however....

Highly targeted CRISPR delivery advances gene editing in living animals

February 1, 2024

Most approved gene therapies today, including those involving CRISPR-Cas9, work their magic on cells removed from the body, after which the edited cells are returned to the patient.

This technique is ideal for targeting blood cells and is currently the method employed in newly approved CRISPR gene therapies for blood diseases like sickle cell anemia, in which edited blood cells are reinfused in patients after their bone marrow has been destroyed by chemotherapy.

A new, precision-targeted delivery method for CRISPR-Cas9,...

Sparrows uniquely adapted to Bay Area marshes are losing their uniqueness

January 24, 2024

The temperate climate of the San Francisco Bay Area has always attracted immigrants — animals and humans — that have had unpredictable impacts on those already living in the area.

For the bay's Savannah sparrow, a subspecies that lives in salty tidal marshes, increased immigration of its inland cousins over the past century has definitely been bad news.

A new genomic analysis of Savannah sparrows (Passerculus sandwichensis) from around the state — many of them collected as far back as 1889, their pelts stored in the Museum of Vertebrate Zoology at the University of California...

Neanderthals and humans lived side by side in Northern Europe 45,000 years ago

January 31, 2024

The evidence that Homo sapiens and Homo neanderthalensis lived side by side is consistent with genomic evidence that the two species occasionally interbred. It also feeds the suspicion that the invasion of Europe and Asia by modern humans some 50,000 years ago helped drive Neanderthals, which had occupied the area for more than 500,000 years, to extinction.

The genetic analysis, along with an archaeological and isotopic analysis and radiocarbon dating of the Ranis site, are detailed in a trio of papers appearing today in the journals Nature and Nature Ecology and Evolution.

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New CRISPR Center brings hope for rare and deadly genetic diseases

January 22, 2024

Children and adults with rare, deadly genetic diseases have fresh hope for curative therapies, thanks to a new collaboration between the Innovative Genomics Institute (IGI) and Danaher Corporation, a global life sciences and diagnostics innovator.

The new Danaher-IGI Beacon for CRISPR Cures center will use genome editing to address potentially hundreds of diseases, including rare genetic disorders that have no cure. The goal is to ensure treatments can be developed and brought to patients more quickly and efficiently.

The IGI comprises genetics researchers and clinician...

New Brilliance of Berkeley course introduces undergrads to 28 luminaries — in one semester

January 19, 2024

With so much brilliance at UC Berkeley — from headline-grabbing research to stellar faculty members across disciplines — it’s impossible for undergraduates, many scouting for their academic passions, to sample it all while on campus.

But this week, a new spring semester course, Brilliance of Berkeley, kicks off with space for 744 in-person participants and 5,000 more...

Announcing a New Department of Neuroscience

January 8, 2024

Dear Friends of The Division of Biological Sciences,

I am excited to announce that UC Berkeley’s Division of Biological Sciences is launching its first new department in more than three decades. The Department of Neuroscience will create a holistic center for students and researchers to examine the brain and the rest of the nervous system.


With this move, we will be able to begin accepting undergraduate students into a new neuroscience major. We are also planning to expand our cluster of graduate students.

Neuroscience has a
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Rethinking the way we think about thinking: A Q&A with Dan Feldman

January 4, 2024

Photo of Dan Feldman

Neuroscience is in a historic era of major discovery, according to Dan Feldman, a professor of neurobiology at UC Berkeley.

For years, neuroscience has steadily grown as a major strength at Berkeley. Now...

Pacific kelp forests are far older than we thought

January 16, 2024

The unique underwater kelp forests that line the Pacific Coast support a varied ecosystem that was thought to have evolved along with the kelp over the past 14 million years.

But a new study shows that kelp flourished off the Northwest Coast more than 32 million years ago, long before the appearance of modern groups of marine mammals, sea urchins, birds and bivalves that today call the forests home.

The much greater age of these coastal kelp forests, which today are a rich ecosystem supporting otters, sea lions, seals, and many birds, fish and crustaceans, means that they...

23 L&S News Highlights From 2023

December 18, 2023
Looking back on another outstanding year, Berkeley Letters & Science has compiled “23 L&S Highlights of 2023”—a recap of accomplishments from the L&S community this year. Here are just a handful of the many stories demonstrating the extraordinary work of L&S students, faculty, staff, and alumni. Enjoy! Milestones & Highlights

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