Search-and-rescue dogs are prized for their ability to sniff out a hiker buried in deep snow. But how exactly do their noses work? UC Berkeley neuroscientist Lucia Jacobs is exploring the smell navigation mechanics of tracking dogs as well as smaller animals who use a similar olfactory GPS. Her research was featured on the PBS NewsHour Aug. 16, and is highlighted in the video below.
CRISPR-Cas9 is the go-to technique for knocking out genes in human cell lines to discover what the genes do, but the efficiency with which it disables genes can vary immensely. UC Berkeley researchers have now found a way to boost the efficiency with which CRISPR-Cas9 cuts and disables genes up to fivefold, in most types of human cells, making it easler to create and study knockout cell lines and, potentially, disable a mutant gene as a form of human therapy.
Most cancer drugs are designed to halt cell growth, the hallmark of cancer, and one popular target is the pathway that controls the production of a cell’s thousands of proteins. UC Berkeley researchers have now found a promising new drug target within that pathway that is appealing, in part, because it appears to control production of only a few percent of the body’s many proteins, those critical to regulating the growth and proliferation of cells.
IST is revamping the server infrastructure underpinning our departmental shared drives. This will cause a brief downtime of up to 3 hours when the L&S data is migrated. The change is tentatively scheduled for Thursday, 8/11 at 6:30 PM. Please let us know if this will cause any problems by emailing firstname.lastname@example.org.
A new comparison of the gut microbiomes of humans, chimps (our closest ancestor), bonobos and gorillas shows that the evolution of two of the major families of bacteria in these apes’ guts exactly parallels the evolution of their hosts.
UC San Francisco and UC Berkeley researchers have mapped out how the Zika virus infects the developing fetus, and have found an antibiotic that blocks these routes of infection, at least in human tissue culture and placental explants.