Protein Transcription Factor T F I I D

Three-dimensional reconstruction of human transcription factor T F I I D (blue), bound to factors T F I I A (magenta) and T F I I B (green). This protein complex is essential for gene expression and regulation. The reconstruction was obtained using electron microscopy and single-particle image analysis of 4000 images of the complex by postdoctoral fellow Frank Andel in Eva Nogales's lab in the Department of Molecular and Cell Biology.

Photo submitted by Eva Nogales